Economic Evaluations Term Paper Example | Topics and Well Written Essays - 500 words

Economic Evaluations - Term Paper Example Estimates indicate that the cost of inpatient care for a case of chronic malaria ranges between US$ 12 and US$ 75 and this creates a substantial burden on inadequate resource base (Lubell et al., 2011). For al long time, Quinine continues to be vital the treatment of malaria in sub-Saharan Africa as well as other malaria prevalent areas. Contemporary studies indicate that in Uganda, doctors prescribed Quinine in approximately ninety percent of children under the age of five years diagnosed with mild malaria. These studies also indicate that the administration of Quinine in these children helped to reduce mortality to up to forty five percent from sixty seven percent (Achan et al., 2011). Quinine not only helps in managing mild malaria cases but it also remains the most widely used drug to treat severe malaria in sub-Saharan Africa. Parenteral quinine is very cheap since it costs only US$ 0.27 per ampoule and is extensively accessible in health systems across Africa. Its administration occurs either intravenously or intramuscularly, three times daily (Lubell et al., 2011). Quinine dispensed intravenously or with the direction of a study doctor for a 7-day period is an extremely successful treatment in sub-Saharan Africa, attaining cure rates of roughly 90%. However, the major impediment for efficient quinine therapy might be compliance to the full treatment course. In addition, Quinine imposes considerable side effects predominantly in extended treatment courses (Adegnika et al., 2005). Assessments of various quinine dosage routines have exposed fascinating trends even with seven-day treatment periods. For instance, doses of 10 mg/kg/day administered twice per day for 7 days often displayed failures of treatment in day 28 with high rates approximately 30%. In addition, increasing the quinine prescribed amount to 15 mg/kg per day or 20 mg/kg daily enhanced treatment effects, with rates of failure occurring at 8% and 14%.